Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 213
Gene Symbol: ALB
ALB
0.100 Biomarker disease BEFREE Our aim was to explore the effect of two different priming strategies (artificial colloid only vs. artificial colloid combined with human serum albumin) on the prognosis of children weighing less than 5 kg undergoing on-pump congenital heart disease (CHD) surgery. 31494945 2020
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12
0.100 Biomarker disease BEFREE Ticagrelor is an antiplatelet agent used for treatment of coronary artery disease via inhibition of the P2Y12 receptor. 31662237 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE In multivariate analyses, the GNRI, age, ankle-brachial pressure index (ABPI), critical limb ischemia, estimated glomerular filtration rate (eGFR), and C-reactive protein (CRP) were independent factors associated with OS, and GNRI, age, ABPI, coronary artery disease, diabetes mellitus, eGFR, and CRP were associated with MACE and MACLE (all p<0.05). 31217396 2020
Entrez Id: 10370
Gene Symbol: CITED2
CITED2
0.080 GeneticVariation disease BEFREE Gene mutations in CITED2 lead to a series of cardiac malformations and congenital heart defects (CHD). 31515672 2020
Entrez Id: 283297
Gene Symbol: OR10A4
OR10A4
0.080 GeneticVariation disease BEFREE The haptoglobin (Hp) 2-2 genotype has been shown to increase the risk of coronary artery disease, kidney dysfunction and mortality from cardiovascular and renal causes in type 1 diabetes (T1D). 31529337 2020
Entrez Id: 7391
Gene Symbol: USF1
USF1
0.080 GeneticVariation disease BEFREE We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family. 31725952 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
0.070 GeneticVariation disease BEFREE Does NLRP3 polymorphisms play a role in the aetiology of coronary artery disease? 31639433 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.070 Biomarker disease BEFREE Upregulation of microRNA-218 reduces cardiac microvascular endothelial cells injury induced by coronary artery disease through the inhibition of HMGB1. 31566720 2020
Entrez Id: 6283
Gene Symbol: S100A12
S100A12
0.060 Biomarker disease BEFREE In addition, recent study showed that serum S100A12 can predict future cardiovascular events, highlighting that S100A12 is likely to be a potential biomarker of therapeutic efficacy and disease progression in coronary heart disease. 31794767 2020
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
0.050 Biomarker disease BEFREE In multivariate logistic regression, compared with the people in the lowest ACE2 quartile, those in the highest quartile had an OR of 4.33 (95% CI 1.20-15.61) for the CHD (P for trend = 0.025), the OR was 5.94 (95% CI 1.08-32.51) for the third ACE2 quartile and 9.58 (95% CI 1.61-56.95) for the highest ACE2 quartile after adjusting for potential confounders (P for trend = 0.022). 31359146 2020
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.050 GeneticVariation disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 GeneticVariation disease BEFREE Assessing the value of coronary artery computed tomography as the first-line anatomical test for stable patients with indications for invasive angiography due to suspected coronary artery disease. Initial cost analysis in the CAT-CAD randomized trial. 31780142 2020
Entrez Id: 55902
Gene Symbol: ACSS2
ACSS2
0.050 GeneticVariation disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 5478
Gene Symbol: PPIA
PPIA
0.050 AlteredExpression disease BEFREE Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease. 31519036 2020
Entrez Id: 23659
Gene Symbol: PLA2G15
PLA2G15
0.050 GeneticVariation disease BEFREE Information on the relationship between circulating cholesteryl ester transfer protein (CETP) levels and coronary heart disease (CHD) incidence (and also, therefore, acute coronary syndrome [ACS]) is conflicting. 31504738 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.040 GeneticVariation disease BEFREE Mortality <1 year was highest in PRISm, often having cardiovascular comorbidity (heart failure or coronary heart disease; 70.0%).PRISm is associated with increased mortality and this population encompasses at least three distinct subsets: one that develops COPD during follow-up, a second with high cardiovascular burden and early mortality, and a third with persistent PRISm and normal age-related lung function decline. 31601717 2020
Entrez Id: 51206
Gene Symbol: GP6
GP6
0.040 Biomarker disease BEFREE We found that the GPVI promoter region in leukocytes from CHD patients was hypomethylated and the expression of GPVI at the mRNA and protein level was elevated in CHD patients. 31783053 2020
Entrez Id: 375704
Gene Symbol: ENHO
ENHO
0.040 Biomarker disease BEFREE Adropin: Connection between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease. 31291637 2020
Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
0.030 Biomarker disease BEFREE Epicardial adipose tissue volume and annexin A2/fetuin-A signalling are linked to coronary calcification in advanced coronary artery disease: Computed tomography and proteomic biomarkers from the EPICHEART study. 31783201 2020
Entrez Id: 27178
Gene Symbol: IL37
IL37
0.030 AlteredExpression disease BEFREE Serum levels of IL‑37 were associated with the levels of IL‑17, IL‑6, and TNF‑α, and clinical indexes such as the left ventricular ejection fraction (LVEF), amino‑N‑terminal pro‑plasma brain natriuretic peptide (NT‑proBNP) levels, and cardiac troponin T (cTnT) levels in CHD patients. 31746393 2020
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.030 Biomarker disease BEFREE Effect of Empagliflozin on Erythropoietin Levels, Iron Stores and Red Blood Cell Morphology in Patients with Type 2 Diabetes and Coronary Artery Disease. 31707794 2020
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.030 Biomarker disease BEFREE However, little is known about the relationship between the cTnI and postoperative course after the congenital heart disease (CHD) operation. 31522246 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.020 Biomarker disease BEFREE PTEN inhibition attenuates endothelial cell apoptosis in coronary heart disease via modulating the AMPK-CREB-Mfn2-mitophagy signaling pathway. 31654396 2020
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.020 Biomarker disease BEFREE The object of present study was to investigate the association of circulating levels of ACE2, Ang-(1-7) and Ang-(1-9) with coronary heart disease (CHD) defined by coronary angiography (CAG). 31359146 2020
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.010 Biomarker disease BEFREE Subjects with low COL1A1, low BMP-6, and high IL-6Rα levels had a hazards ratio of 5.097 for incident CHD risk (p = 0.019), compared with those without. 31812227 2020